cancer, Inhibitor, K Ras PDEdelta IN 1, inhibit, K-Ras-PDEdelta-IN-1, KRasPDEdeltaIN1, K-Ras-PDEdelta-IN-1, PDEdelta, PDE, phosphodiesterase, Phosphodiesterase (PDE), pyrazolopyridazinone-based
K-Ras-PDEdelta-IN-1 is a high-affinity inhibitor (Kd = 8 nM) that targets the farnesyl-binding site of PDEdelta, disrupting the K-Ras-PDEdelta interaction. This tool compound is valuable for in vitro biochemical studies and cellular research exploring oncogenic Ras signaling pathways and potential therapeutic strategies.
Molekulargewicht:
447.5
Reinheit:
99.74% (May vary between batches)
CAS Nummer:
[1841464-21-8]
Formel:
C25H26FN5O2
Target-Kategorie:
PDE
Anwendungsbeschreibung:
Solubility: DMSO:4.48 mg/mL (10.01 mM)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten