ML318 is a potent biaryl nitrile inhibitor of the PvdQ acylase, exhibiting an IC50 of 20 nM. It effectively suppresses Pseudomonas aeruginosa (PAO1) growth (IC50 = 19 µM) and pyoverdine siderophore production, particularly under iron-limiting conditions, making it a valuable tool for studying quorum sensing and virulence pathways in vitro.
Molekulargewicht:
280.22
Reinheit:
98.93% (May vary between batches)
CAS Nummer:
[1610516-67-0]
Formel:
C14H8F4N2
Target-Kategorie:
Antibiotic
Anwendungsbeschreibung:
Solubility: DMSO:60 mg/mL (214.12 mM)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten