ML318 is a potent biaryl nitrile inhibitor of the PvdQ acylase, exhibiting an IC50 of 20 nM. It effectively suppresses Pseudomonas aeruginosa (PAO1) growth (IC50 = 19 µM) and pyoverdine siderophore production, particularly under iron-limiting conditions, making it a valuable tool for studying quorum sensing and virulence pathways in vitro.
Molecular Weight:
280.22
Purity:
98.93% (May vary between batches)
CAS Number:
[1610516-67-0]
Formula:
C14H8F4N2
Target:
Antibiotic
Application Notes:
Solubility: DMSO:60 mg/mL (214.12 mM)
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