Afuresertib hydrochloride, CAS [[1047645-82-8]]

Produktübersicht

• Artikelname: Afuresertib hydrochloride, CAS [[1047645-82-8]]
• Artikelnummer: BYT-ORB1299415
• Hersteller Artikelnummer: orb1299415
• Alternativnummer: BYT-ORB1299415-1, BYT-ORB1299415-10, BYT-ORB1299415-100, BYT-ORB1299415-2, BYT-ORB1299415-200, BYT-ORB1299415-25, BYT-ORB1299415-5, BYT-ORB1299415-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: inhibit, GSK2110183, GSK-2110183, GSK 2110183, Inhibitor, Akt, Afuresertib, Afuresertib Hydrochloride, Afuresertib hydrochloride, Protein kinase C, Protein kinase B, Rho-kinase, Rho-associated kinase, Rho-associated protein kinase, ROK, ROCK, PKB, PKC

Produktbeschreibung

Afuresertib hydrochloride is a potent and selective pan-Akt kinase inhibitor, exhibiting Kis of 0.08, 2, and 2.6 nM for Akt1, Akt2, and Akt3, respectively. It is widely used in preclinical research to investigate the PI3K/Akt signaling pathway in cancer, with applications in both in vitro cellular assays and in vivo xenograft models.

Produkteigenschaften

• Molekulargewicht: 463.8
• Reinheit: >99.99% (May vary between batches)
• CAS Nummer: [1047645-82-8]
• Formel: C18H18Cl3FN4OS
• Target-Kategorie: Akt,PKC,ROCK

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.62 mM),DMSO:100 mg/mL (215.61 mM)