Afuresertib hydrochloride, CAS [[1047645-82-8]]

Product Overview

• Article Name: Afuresertib hydrochloride, CAS [[1047645-82-8]]
• Biozol Catalog Number: BYT-ORB1299415
• Supplier Catalog Number: orb1299415
• Alternative Catalog Number: BYT-ORB1299415-1, BYT-ORB1299415-10, BYT-ORB1299415-100, BYT-ORB1299415-2, BYT-ORB1299415-200, BYT-ORB1299415-25, BYT-ORB1299415-5, BYT-ORB1299415-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: inhibit, GSK2110183, GSK-2110183, GSK 2110183, Inhibitor, Akt, Afuresertib, Afuresertib Hydrochloride, Afuresertib hydrochloride, Protein kinase C, Protein kinase B, Rho-kinase, Rho-associated kinase, Rho-associated protein kinase, ROK, ROCK, PKB, PKC

Product Description

Afuresertib hydrochloride is a potent and selective pan-Akt kinase inhibitor, exhibiting Kis of 0.08, 2, and 2.6 nM for Akt1, Akt2, and Akt3, respectively. It is widely used in preclinical research to investigate the PI3K/Akt signaling pathway in cancer, with applications in both in vitro cellular assays and in vivo xenograft models.

Product Properties

• Molecular Weight: 463.8
• Purity: >99.99% (May vary between batches)
• CAS Number: [1047645-82-8]
• Formula: C18H18Cl3FN4OS
• Target: Akt,PKC,ROCK

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.62 mM),DMSO:100 mg/mL (215.61 mM)