IOX4 is a highly potent and selective inhibitor of prolyl hydroxylase domain protein 2 (PHD2/EGLN1) with an IC50 of 1.6 nM. It is widely used in hypoxia-related research to stabilize HIF-alpha in vitro and has been applied in studies investigating ischemic and inflammatory disease models in vivo.
Molekulargewicht:
328.33
Reinheit:
99.97% (May vary between batches)
CAS Nummer:
[1154097-71-8]
Formel:
C15H16N6O3
Target-Kategorie:
HIF/HIF Prolyl-Hydroxylase
Anwendungsbeschreibung:
Solubility: DMSO:83.33 mg/mL (253.8 mM)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten