IOX4 is a highly potent and selective inhibitor of prolyl hydroxylase domain protein 2 (PHD2/EGLN1) with an IC50 of 1.6 nM. It is widely used in hypoxia-related research to stabilize HIF-alpha in vitro and has been applied in studies investigating ischemic and inflammatory disease models in vivo.
Molecular Weight:
328.33
Purity:
99.97% (May vary between batches)
CAS Number:
[1154097-71-8]
Formula:
C15H16N6O3
Target:
HIF/HIF Prolyl-Hydroxylase
Application Notes:
Solubility: DMSO:83.33 mg/mL (253.8 mM)
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