Theliatinib, CAS [[1353644-70-8]]

Produktübersicht

• Artikelname: Theliatinib, CAS [[1353644-70-8]]
• Artikelnummer: BYT-ORB1299921
• Hersteller Artikelnummer: orb1299921
• Alternativnummer: BYT-ORB1299921-1, BYT-ORB1299921-1, BYT-ORB1299921-10, BYT-ORB1299921-100, BYT-ORB1299921-25, BYT-ORB1299921-5, BYT-ORB1299921-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: HMPL309, HMPL-309, HMPL 309, Inhibitor, HER1, ERK, esophageal, ErbB-1, Epidermal growth factor receptor, EGFR, inhibit, orally, anti-tumor, ATP-competitive, cancer, AKT, Theliatinib, Xiliertinib, phosphorylation

Produktbeschreibung

Theliatinib is a potent and highly selective EGFR inhibitor, exhibiting a Ki of 0.05 nM for wild-type EGFR. It demonstrates anti-tumor activity in research models, with IC50 values of 3 nM and 22 nM against EGFR and the EGFR T790M/L858R mutant, respectively. This compound is applied in preclinical oncology research for investigating EGFR-driven cancers both in vitro and in vivo.

Produkteigenschaften

• Molekulargewicht: 442.51
• Reinheit: 99.67% (May vary between batches)
• CAS Nummer: [1353644-70-8]
• Formel: C25H26N6O2
• Target-Kategorie: EGFR

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: DMSO:47 mg/mL (106.21 mM)