Niraparib tosylate, CAS [[1038915-73-9]]

Produktübersicht

• Artikelname: Niraparib tosylate, CAS [[1038915-73-9]]
• Artikelnummer: BYT-ORB1300371
• Hersteller Artikelnummer: orb1300371
• Alternativnummer: BYT-ORB1300371-1, BYT-ORB1300371-1, BYT-ORB1300371-5, BYT-ORB1300371-10, BYT-ORB1300371-25, BYT-ORB1300371-50, BYT-ORB1300371-100
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: damage, DNA, breast, Apoptosis, anti-tumor, bioavailable, cancer, Inhibitor, inhibit, lung, poly ADP ribose polymerase, ovarian, Niraparib tosylate, Niraparib Tosylate, Niraparib, Niraparib (MK-4827) tosylate, Niraparib (MK-4827) Tosylate, orally, PARP, PARP1, PARP2, MK 4827, MK 4827 tosylate, MK 4827 Tosylate, MK4827, MK-4827, MK-4827 (tosylate), MK4827 Tosylate, MK-4827 Tosylate

Produktbeschreibung

Niraparib tosylate is a potent and selective inhibitor of PARP1 and PARP2 enzymes, exhibiting IC50 values of 3.8 nM and 2.1 nM, respectively. It is widely used in cancer research, particularly for studying synthetic lethality in BRCA-deficient models, and has demonstrated efficacy in both in vitro cellular assays and in vivo tumor xenograft studies.

Produkteigenschaften

• Molekulargewicht: 492.59
• Reinheit: 99.87% (May vary between batches)
• CAS Nummer: [1038915-73-9]
• Formel: C19H20N4OC7H8O3S
• Target-Kategorie: PARP,Apoptosis

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: Ethanol:< 1 mg/mL (insoluble or slightly soluble),DMSO:91 mg/mL (184.74 mM),H2O:< 1 mg/mL (insoluble or slightly soluble)