Niraparib tosylate, CAS [[1038915-73-9]]

Product Overview

• Article Name: Niraparib tosylate, CAS [[1038915-73-9]]
• Biozol Catalog Number: BYT-ORB1300371
• Supplier Catalog Number: orb1300371
• Alternative Catalog Number: BYT-ORB1300371-1, BYT-ORB1300371-1, BYT-ORB1300371-5, BYT-ORB1300371-10, BYT-ORB1300371-25, BYT-ORB1300371-50, BYT-ORB1300371-100
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: damage, DNA, breast, Apoptosis, anti-tumor, bioavailable, cancer, Inhibitor, inhibit, lung, poly ADP ribose polymerase, ovarian, Niraparib tosylate, Niraparib Tosylate, Niraparib, Niraparib (MK-4827) tosylate, Niraparib (MK-4827) Tosylate, orally, PARP, PARP1, PARP2, MK 4827, MK 4827 tosylate, MK 4827 Tosylate, MK4827, MK-4827, MK-4827 (tosylate), MK4827 Tosylate, MK-4827 Tosylate

Product Description

Niraparib tosylate is a potent and selective inhibitor of PARP1 and PARP2 enzymes, exhibiting IC50 values of 3.8 nM and 2.1 nM, respectively. It is widely used in cancer research, particularly for studying synthetic lethality in BRCA-deficient models, and has demonstrated efficacy in both in vitro cellular assays and in vivo tumor xenograft studies.

Product Properties

• Molecular Weight: 492.59
• Purity: 99.87% (May vary between batches)
• CAS Number: [1038915-73-9]
• Formula: C19H20N4OC7H8O3S
• Target: PARP,Apoptosis

Application Notes

• Application Notes: Solubility: Ethanol:< 1 mg/mL (insoluble or slightly soluble),DMSO:91 mg/mL (184.74 mM),H2O:< 1 mg/mL (insoluble or slightly soluble)