BQ-123, CAS [[136553-81-6]]

Produktübersicht

• Artikelname: BQ-123, CAS [[136553-81-6]]
• Artikelnummer: BYT-ORB1300461
• Hersteller Artikelnummer: orb1300461
• Alternativnummer: BYT-ORB1300461-1,BYT-ORB1300461-5,BYT-ORB1300461-10,BYT-ORB1300461-25,BYT-ORB1300461-50,BYT-ORB1300461-100
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: cells, BQ 123, BQ123, BQ-123, blood, artery, EndothelinReceptor, Endothelin Receptor, Endothelin A receptor, Inhibitor, inhibit, muscle, smooth, pulmonary, pressure

Produktbeschreibung

BQ-123 is a potent and selective endothelin A (ETA) receptor antagonist with an IC50 of 7.3 nM. This compound is a valuable research tool for investigating the role of ET-1 signaling in cardiovascular diseases, pulmonary hypertension, and cancer, as demonstrated in various in vitro and in vivo studies. It has been evaluated in Phase 2 clinical trials.

Produkteigenschaften

• Molekulargewicht: 610.7
• Reinheit: 99.22% (May vary between batches)
• CAS Nummer: [136553-81-6]
• Formel: C31H42N6O7
• Target-Kategorie: Endothelin Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: Ethanol:12 mg/mL (19.65 mM),DMSO:93 mg/mL (152.28 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.19 mM),H2O:< 1 mg/mL (insoluble or slightly soluble)