BQ-123, CAS [[136553-81-6]]

Product Overview

• Article Name: BQ-123, CAS [[136553-81-6]]
• Biozol Catalog Number: BYT-ORB1300461
• Supplier Catalog Number: orb1300461
• Alternative Catalog Number: BYT-ORB1300461-1,BYT-ORB1300461-5,BYT-ORB1300461-10,BYT-ORB1300461-25,BYT-ORB1300461-50,BYT-ORB1300461-100
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: cells, BQ 123, BQ123, BQ-123, blood, artery, EndothelinReceptor, Endothelin Receptor, Endothelin A receptor, Inhibitor, inhibit, muscle, smooth, pulmonary, pressure

Product Description

BQ-123 is a potent and selective endothelin A (ETA) receptor antagonist with an IC50 of 7.3 nM. This compound is a valuable research tool for investigating the role of ET-1 signaling in cardiovascular diseases, pulmonary hypertension, and cancer, as demonstrated in various in vitro and in vivo studies. It has been evaluated in Phase 2 clinical trials.

Product Properties

• Molecular Weight: 610.7
• Purity: 99.22% (May vary between batches)
• CAS Number: [136553-81-6]
• Formula: C31H42N6O7
• Target: Endothelin Receptor

Application Notes

• Application Notes: Solubility: Ethanol:12 mg/mL (19.65 mM),DMSO:93 mg/mL (152.28 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.19 mM),H2O:< 1 mg/mL (insoluble or slightly soluble)