Tyrphostin AG 879, CAS [[148741-30-4]]
Artikelnummer:
BYT-ORB1300532
Produktübersicht
Artikelname:
Tyrphostin AG 879, CAS [[148741-30-4]]
Artikelnummer:
BYT-ORB1300532
Hersteller Artikelnummer:
orb1300532
Alternativnummer:
BYT-ORB1300532-5,BYT-ORB1300532-1,BYT-ORB1300532-10,BYT-ORB1300532-25,BYT-ORB1300532-50,BYT-ORB1300532-100
Hersteller:
Biorbyt
Kategorie:
Biochemikalien
Alternative Synonym:
ErbB-1, ErbB2, EGFR, Epidermal growth factor receptor, HER2-Neu, HER1, Inhibitor, p75, inhibit, Apoptosis, Antitumor, antiproliferation, AG879, AG-879, AG 879, PDGFR, phosphorylation, Tyrphostin AG 879, Tyrphostin AG879, Tyrphostin AG-879, tyrosine, Tropomyosin related kinase receptor, Trkreceptor, Trk, Trk receptor, Trk Receptor, TrKA
Produktbeschreibung
Tyrphostin AG 879 is a selective inhibitor of the HER2/ErbB2 tyrosine kinase, demonstrating potent activity with an IC50 of 1 µM. It exhibits 100- to 500-fold selectivity for HER2 over EGFR and PDGFR, making it a valuable tool for investigating HER2-driven signaling in cancer research, both in cellular and animal models.
Produkteigenschaften
Molekulargewicht:
316.46
Reinheit:
99.05% (May vary between batches)
CAS Nummer:
[148741-30-4]
Formel:
C18H24N2OS
Target-Kategorie:
Apoptosis,Trk receptor,HER,PDGFR,EGFR
Anwendungsbeschreibung
Anwendungsbeschreibung:
Solubility: DMSO:31.7 mg/mL (100.17 mM),Ethanol:7.9 mg/mL (24.96 mM)
