Tyrphostin AG 879, CAS [[148741-30-4]]

Product Overview

• Article Name: Tyrphostin AG 879, CAS [[148741-30-4]]
• Biozol Catalog Number: BYT-ORB1300532
• Supplier Catalog Number: orb1300532
• Alternative Catalog Number: BYT-ORB1300532-5,BYT-ORB1300532-1,BYT-ORB1300532-10,BYT-ORB1300532-25,BYT-ORB1300532-50,BYT-ORB1300532-100
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: ErbB-1, ErbB2, EGFR, Epidermal growth factor receptor, HER2-Neu, HER1, Inhibitor, p75, inhibit, Apoptosis, Antitumor, antiproliferation, AG879, AG-879, AG 879, PDGFR, phosphorylation, Tyrphostin AG 879, Tyrphostin AG879, Tyrphostin AG-879, tyrosine, Tropomyosin related kinase receptor, Trkreceptor, Trk, Trk receptor, Trk Receptor, TrKA

Product Description

Tyrphostin AG 879 is a selective inhibitor of the HER2/ErbB2 tyrosine kinase, demonstrating potent activity with an IC50 of 1 µM. It exhibits 100- to 500-fold selectivity for HER2 over EGFR and PDGFR, making it a valuable tool for investigating HER2-driven signaling in cancer research, both in cellular and animal models.

Product Properties

• Molecular Weight: 316.46
• Purity: 99.05% (May vary between batches)
• CAS Number: [148741-30-4]
• Formula: C18H24N2OS
• Target: Apoptosis,Trk receptor,HER,PDGFR,EGFR

Application Notes

• Application Notes: Solubility: DMSO:31.7 mg/mL (100.17 mM),Ethanol:7.9 mg/mL (24.96 mM)