Refametinib, CAS [[923032-37-5]]

Produktübersicht

• Artikelname: Refametinib, CAS [[923032-37-5]]
• Artikelnummer: BYT-ORB1300596
• Hersteller Artikelnummer: orb1300596
• Alternativnummer: BYT-ORB1300596-1,BYT-ORB1300596-10,BYT-ORB1300596-100,BYT-ORB1300596-2,BYT-ORB1300596-200,BYT-ORB1300596-25,BYT-ORB1300596-5,BYT-ORB1300596-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: tumor, RDEA119, RDEA-119, Refametinib, RDEA 119, MAP2K, MAPKK, MEK, MEK1, MEK2, Inhibitor, inhibit, Mitogen-activated protein kinase kinase, orally, BAY 869766, BAY 86-97661, BAY869766, BAY-869766, allosteric

Produktbeschreibung

Refametinib (RDEA119) is a potent and selective, ATP-noncompetitive inhibitor of MEK1 and MEK2 kinases, exhibiting IC50 values of 19 nM and 47 nM, respectively. It is widely used in cancer research, demonstrating antitumor activity in both in vitro cellular assays and in vivo models of various malignancies.

Produkteigenschaften

• Molekulargewicht: 572.34
• Reinheit: >99.99% (May vary between batches)
• CAS Nummer: [923032-37-5]
• Formel: C19H20F3IN2O5S
• Target-Kategorie: MEK

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: Ethanol:93 mg/mL (162.49 mM),DMSO:150 mg/mL (262.08 mM),H2O:< 1 mg/mL (insoluble or slightly soluble)