Mitoxantrone, CAS [[65271-80-9]]

Artikelnummer: BYT-ORB1300634
Artikelname: Mitoxantrone, CAS [[65271-80-9]]
Artikelnummer: BYT-ORB1300634
Hersteller Artikelnummer: orb1300634
Alternativnummer: BYT-ORB1300634-1, BYT-ORB1300634-100, BYT-ORB1300634-200, BYT-ORB1300634-25, BYT-ORB1300634-50
Hersteller: Biorbyt
Kategorie: Biochemikalien
Alternative Synonym: Topo II, Topoisomerase, Protein kinase C, PKC, Apoptosis, antitumor, B-CLL cells, breast cancer, NSC-301739, NSC301739, lymphocytes, Mitoxantrone, mitozantrone, Orthopoxvirus, NSC 301739, inhibit, Inhibitor, HL60 cells, MCF-7, leukaemia, Endogenous Metabolite
Mitoxantrone is a dual Topo II and PKC inhibitor (IC50=8.5 µM) with established antitumor activity. It is widely used in research models for leukemia, breast cancer, and hepatocellular carcinoma, supporting both in vitro mechanistic studies and in vivo efficacy experiments.
Molekulargewicht: 444.48
Reinheit: 98.74% (May vary between batches)
CAS Nummer: [65271-80-9]
Formel: C22H28N4O6
Target-Kategorie: Topoisomerase,Virus Protease,PKC,Apoptosis,Endogenous Metabolite
Anwendungsbeschreibung: Solubility: Ethanol:< 1 mg/mL (insoluble or slightly soluble),5% DMSO+95% Saline:2.37 mg/mL (5.33 mM),H2O:< 1 mg/mL (insoluble or slightly soluble),DMSO:88 mg/mL (197.98 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:0.15 mg/mL (0.34 mM)