Mitoxantrone, CAS [[65271-80-9]]

Product Overview

• Article Name: Mitoxantrone, CAS [[65271-80-9]]
• Biozol Catalog Number: BYT-ORB1300634
• Supplier Catalog Number: orb1300634
• Alternative Catalog Number: BYT-ORB1300634-1, BYT-ORB1300634-100, BYT-ORB1300634-200, BYT-ORB1300634-25, BYT-ORB1300634-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Topo II, Topoisomerase, Protein kinase C, PKC, Apoptosis, antitumor, B-CLL cells, breast cancer, NSC-301739, NSC301739, lymphocytes, Mitoxantrone, mitozantrone, Orthopoxvirus, NSC 301739, inhibit, Inhibitor, HL60 cells, MCF-7, leukaemia, Endogenous Metabolite

Product Description

Mitoxantrone is a dual Topo II and PKC inhibitor (IC50=8.5 µM) with established antitumor activity. It is widely used in research models for leukemia, breast cancer, and hepatocellular carcinoma, supporting both in vitro mechanistic studies and in vivo efficacy experiments.

Product Properties

• Molecular Weight: 444.48
• Purity: 98.74% (May vary between batches)
• CAS Number: [65271-80-9]
• Formula: C22H28N4O6
• Target: Topoisomerase,Virus Protease,PKC,Apoptosis,Endogenous Metabolite

Application Notes

• Application Notes: Solubility: Ethanol:< 1 mg/mL (insoluble or slightly soluble),5% DMSO+95% Saline:2.37 mg/mL (5.33 mM),H2O:< 1 mg/mL (insoluble or slightly soluble),DMSO:88 mg/mL (197.98 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:0.15 mg/mL (0.34 mM)