GW 5074 is a potent and selective c-Raf inhibitor (IC50=9 nM) with demonstrated utility in studying MAPK/ERK signaling pathways in cellular and animal models of cancer and neurological diseases. It exhibits high specificity, showing no activity against a panel of other kinases including JNK, MEK, and VEGFR2.
Molekulargewicht:
520.94
Reinheit:
99.32% (May vary between batches)
CAS Nummer:
[220904-83-6]
Formel:
C15H8Br2INO2
Target-Kategorie:
Raf,Apoptosis
Anwendungsbeschreibung:
Solubility: DMSO:83.33 mg/mL (159.96 mM),Ethanol:< 1 mg/mL (insoluble or slightly soluble),H2O:< 1 mg/mL (insoluble or slightly soluble)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten