GW 5074, CAS [[220904-83-6]]

Product Overview

• Article Name: GW 5074, CAS [[220904-83-6]]
• Biozol Catalog Number: BYT-ORB1300692
• Supplier Catalog Number: orb1300692
• Alternative Catalog Number: BYT-ORB1300692-1, BYT-ORB1300692-10, BYT-ORB1300692-100, BYT-ORB1300692-2, BYT-ORB1300692-25, BYT-ORB1300692-5, BYT-ORB1300692-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: C-Raf, Apoptosis, inhibit, Inhibitor, GW5074, GW-5074, GW 5074, Raf, Raf kinases, Raf1 Kinase Inhibitor I

Product Description

GW 5074 is a potent and selective c-Raf inhibitor (IC50=9 nM) with demonstrated utility in studying MAPK/ERK signaling pathways in cellular and animal models of cancer and neurological diseases. It exhibits high specificity, showing no activity against a panel of other kinases including JNK, MEK, and VEGFR2.

Product Properties

• Molecular Weight: 520.94
• Purity: 99.32% (May vary between batches)
• CAS Number: [220904-83-6]
• Formula: C15H8Br2INO2
• Target: Raf,Apoptosis

Application Notes

• Application Notes: Solubility: DMSO:83.33 mg/mL (159.96 mM),Ethanol:< 1 mg/mL (insoluble or slightly soluble),H2O:< 1 mg/mL (insoluble or slightly soluble)