Glasdegib, CAS [[1095173-27-5]]
Artikelnummer:
BYT-ORB1300702
Produktübersicht
Artikelname:
Glasdegib, CAS [[1095173-27-5]]
Artikelnummer:
BYT-ORB1300702
Hersteller Artikelnummer:
orb1300702
Alternativnummer:
BYT-ORB1300702-1, BYT-ORB1300702-1, BYT-ORB1300702-10, BYT-ORB1300702-100, BYT-ORB1300702-25, BYT-ORB1300702-5, BYT-ORB1300702-50
Hersteller:
Biorbyt
Kategorie:
Biochemikalien
Alternative Synonym:
Smo, Smoothened, PF 04449913, PF04449913, PF-04449913, Inhibitor, inhibit, Glasdegib, Hedgehog
Produktbeschreibung
Glasdegib (PF-04449913) is a potent, orally active Smoothened (Smo) antagonist with an IC50 of 5 nM. This small molecule inhibitor is used in research to study Hedgehog signaling pathway dysregulation in cancers, demonstrating activity in both in vitro assays and in vivo models.
Produkteigenschaften
Molekulargewicht:
374.44
Reinheit:
98.72% (May vary between batches)
CAS Nummer:
[1095173-27-5]
Formel:
C21H22N6O
Target-Kategorie:
Hedgehog/Smoothened,Smo
Anwendungsbeschreibung
Anwendungsbeschreibung:
Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.34 mM),DMSO:48 mg/mL (128.19 mM),Ethanol:< 1 mg/mL (insoluble or slightly soluble),H2O:< 1 mg/mL (insoluble or slightly soluble)
