Glasdegib, CAS [[1095173-27-5]]
Catalog Number:
BYT-ORB1300702
Product Overview
Article Name:
Glasdegib, CAS [[1095173-27-5]]
Biozol Catalog Number:
BYT-ORB1300702
Supplier Catalog Number:
orb1300702
Alternative Catalog Number:
BYT-ORB1300702-1, BYT-ORB1300702-1, BYT-ORB1300702-10, BYT-ORB1300702-100, BYT-ORB1300702-25, BYT-ORB1300702-5, BYT-ORB1300702-50
Manufacturer:
Biorbyt
Category:
Biochemikalien
Alternative Names:
Smo, Smoothened, PF 04449913, PF04449913, PF-04449913, Inhibitor, inhibit, Glasdegib, Hedgehog
Product Description
Glasdegib (PF-04449913) is a potent, orally active Smoothened (Smo) antagonist with an IC50 of 5 nM. This small molecule inhibitor is used in research to study Hedgehog signaling pathway dysregulation in cancers, demonstrating activity in both in vitro assays and in vivo models.
Product Properties
Molecular Weight:
374.44
Purity:
98.72% (May vary between batches)
CAS Number:
[1095173-27-5]
Formula:
C21H22N6O
Target:
Hedgehog/Smoothened,Smo
Application Notes
Application Notes:
Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.34 mM),DMSO:48 mg/mL (128.19 mM),Ethanol:< 1 mg/mL (insoluble or slightly soluble),H2O:< 1 mg/mL (insoluble or slightly soluble)
