Encorafenib, CAS [[1269440-17-6]]

Produktübersicht

• Artikelname: Encorafenib, CAS [[1269440-17-6]]
• Artikelnummer: BYT-ORB1300725
• Hersteller Artikelnummer: orb1300725
• Alternativnummer: BYT-ORB1300725-1, BYT-ORB1300725-10, BYT-ORB1300725-25, BYT-ORB1300725-5, BYT-ORB1300725-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: Raf, Raf kinases, B-Raf (V600E), Inhibitor, LGX 818, LGX818, LGX-818, Encorafenib, inhibit

Produktbeschreibung

Encorafenib (LGX818) is a potent and selective oral inhibitor of the BRAF V600E mutation, with an IC50 of 0.3 nM. It is widely used in preclinical oncology research, demonstrating significant antitumor activity in both in vitro cellular assays and in vivo models of melanoma and colorectal cancer.

Produkteigenschaften

• Molekulargewicht: 540.01
• Reinheit: 99.83% (May vary between batches)
• CAS Nummer: [1269440-17-6]
• Formel: C22H27ClFN7O4S
• Target-Kategorie: Raf

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble),10% DMSO+40% PEG300+5% Tween 80+45% Saline:9.3 mg/mL (17.22 mM),DMSO:257 mg/mL (475.92 mM),Ethanol:93 mg/mL (172.22 mM)