Cilomilast, CAS [[153259-65-5]]

Produktübersicht

• Artikelname: Cilomilast, CAS [[153259-65-5]]
• Artikelnummer: BYT-ORB1300763
• Hersteller Artikelnummer: orb1300763
• Alternativnummer: BYT-ORB1300763-1, BYT-ORB1300763-10, BYT-ORB1300763-100, BYT-ORB1300763-25, BYT-ORB1300763-5, BYT-ORB1300763-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: COPD, chronic, Cilomilast, disease, anti-inflammatory, Ariflo, asthma, HPDE4, obstructive, LPDE4, PDE4, immunomodulatory, Inhibitor, inhibit, phosphodiesterase, Phosphodiesterase, Phosphodiesterase (PDE), SB 207499, SB207499, SB-207499, pulmonary

Produktbeschreibung

Cilomilast (SB-207499) is a selective PDE4 inhibitor with an IC50 of approximately 110 nM, exhibiting potent anti-inflammatory effects with minimal CNS penetration. It has been investigated in clinical Phase 3 trials for chronic obstructive pulmonary disease (COPD) and studied in models of inflammatory cell activation.

Produkteigenschaften

• Molekulargewicht: 343.42
• Reinheit: 99.52% (May vary between batches)
• CAS Nummer: [153259-65-5]
• Formel: C20H25NO4
• Target-Kategorie: PDE

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble),DMSO:60 mg/mL (174.71 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.82 mM),Ethanol:31 mg/mL (90.27 mM)