Cilomilast, CAS [[153259-65-5]]
Catalog Number:
BYT-ORB1300763
Product Overview
Article Name:
Cilomilast, CAS [[153259-65-5]]
Biozol Catalog Number:
BYT-ORB1300763
Supplier Catalog Number:
orb1300763
Alternative Catalog Number:
BYT-ORB1300763-1, BYT-ORB1300763-10, BYT-ORB1300763-100, BYT-ORB1300763-25, BYT-ORB1300763-5, BYT-ORB1300763-50
Manufacturer:
Biorbyt
Category:
Biochemikalien
Alternative Names:
COPD, chronic, Cilomilast, disease, anti-inflammatory, Ariflo, asthma, HPDE4, obstructive, LPDE4, PDE4, immunomodulatory, Inhibitor, inhibit, phosphodiesterase, Phosphodiesterase, Phosphodiesterase (PDE), SB 207499, SB207499, SB-207499, pulmonary
Product Description
Cilomilast (SB-207499) is a selective PDE4 inhibitor with an IC50 of approximately 110 nM, exhibiting potent anti-inflammatory effects with minimal CNS penetration. It has been investigated in clinical Phase 3 trials for chronic obstructive pulmonary disease (COPD) and studied in models of inflammatory cell activation.
Product Properties
Molecular Weight:
343.42
Purity:
99.52% (May vary between batches)
CAS Number:
[153259-65-5]
Formula:
C20H25NO4
Target:
PDE
Application Notes
Application Notes:
Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble),DMSO:60 mg/mL (174.71 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.82 mM),Ethanol:31 mg/mL (90.27 mM)
