GSK4112, CAS [[1216744-19-2]]
Artikelnummer:
BYT-ORB1302143
Produktübersicht
Artikelname:
GSK4112, CAS [[1216744-19-2]]
Artikelnummer:
BYT-ORB1302143
Hersteller Artikelnummer:
orb1302143
Alternativnummer:
BYT-ORB1302143-1,BYT-ORB1302143-10,BYT-ORB1302143-25,BYT-ORB1302143-50,BYT-ORB1302143-100,BYT-ORB1302143-200
Hersteller:
Biorbyt
Kategorie:
Biochemikalien
Alternative Synonym:
transcription, SR6452, SR-6452, SR 6452, Rev-ErbBalpha, probe, Autophagy, Apoptosis, bmal1, 1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate, hepatic damage, hepatic gene, HepG2, HDAC, gluconeogenesis, GSK 4112, GSK-4112, GSK4112, Fas, Inhibitor, Jo2, inhibit, mice
Produktbeschreibung
GSK4112 (SR6452) is a potent and selective synthetic agonist of the nuclear receptor Rev-erbalpha, demonstrating an EC50 of 0.4 µM. This chemical probe is widely used in vitro and in vivo to investigate circadian rhythm regulation, metabolic pathways, and inflammatory responses linked to Rev-erbalpha biology.
Produkteigenschaften
Molekulargewicht:
396.89
Reinheit:
99.69% (May vary between batches)
CAS Nummer:
[1216744-19-2]
Formel:
C18H21ClN2O4S
Target-Kategorie:
Autophagy,REV-ERB,Apoptosis
Anwendungsbeschreibung
Anwendungsbeschreibung:
Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.52 mM),DMSO:9.9 mg/mL (24.94 mM)