GSK4112, CAS [[1216744-19-2]]
Catalog Number:
BYT-ORB1302143
Product Overview
Article Name:
GSK4112, CAS [[1216744-19-2]]
Biozol Catalog Number:
BYT-ORB1302143
Supplier Catalog Number:
orb1302143
Alternative Catalog Number:
BYT-ORB1302143-1,BYT-ORB1302143-10,BYT-ORB1302143-25,BYT-ORB1302143-50,BYT-ORB1302143-100,BYT-ORB1302143-200
Manufacturer:
Biorbyt
Category:
Biochemikalien
Alternative Names:
transcription, SR6452, SR-6452, SR 6452, Rev-ErbBalpha, probe, Autophagy, Apoptosis, bmal1, 1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate, hepatic damage, hepatic gene, HepG2, HDAC, gluconeogenesis, GSK 4112, GSK-4112, GSK4112, Fas, Inhibitor, Jo2, inhibit, mice
Product Description
GSK4112 (SR6452) is a potent and selective synthetic agonist of the nuclear receptor Rev-erbalpha, demonstrating an EC50 of 0.4 µM. This chemical probe is widely used in vitro and in vivo to investigate circadian rhythm regulation, metabolic pathways, and inflammatory responses linked to Rev-erbalpha biology.
Product Properties
Molecular Weight:
396.89
Purity:
99.69% (May vary between batches)
CAS Number:
[1216744-19-2]
Formula:
C18H21ClN2O4S
Target:
Autophagy,REV-ERB,Apoptosis
Application Notes
Application Notes:
Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.52 mM),DMSO:9.9 mg/mL (24.94 mM)
