CBL0137, CAS [[1197996-80-7]]
Artikelnummer:
BYT-ORB1303131
Produktübersicht
Artikelname:
CBL0137, CAS [[1197996-80-7]]
Artikelnummer:
BYT-ORB1303131
Hersteller Artikelnummer:
orb1303131
Alternativnummer:
BYT-ORB1303131-1, BYT-ORB1303131-1, BYT-ORB1303131-10, BYT-ORB1303131-100, BYT-ORB1303131-25, BYT-ORB1303131-5, BYT-ORB1303131-50
Hersteller:
Biorbyt
Kategorie:
Biochemikalien
Alternative Synonym:
NFkB, NF-kB, NFkappaB, NF-kappaB, p53, CBLC 137, CBL0137, CBL-0137, CBLC137, CBLC-137, CBL 0137, Curaxin 137
Produktbeschreibung
CBL0137 is a metabolically stable curaxin that potently activates p53 and inhibits NF-kappaB by inactivating the FACT complex. It demonstrates broad in vivo anticancer activity, eradicates resistant cancer stem cells, and synergizes with gemcitabine in preclinical pancreatic cancer models.
Produkteigenschaften
Molekulargewicht:
336.43
Reinheit:
99.68% (May vary between batches)
CAS Nummer:
[1197996-80-7]
Formel:
C21H24N2O2
Target-Kategorie:
NF-kappaB,Histone Acetyltransferase,p53,MDM-2/p53
Anwendungsbeschreibung
Anwendungsbeschreibung:
Solubility: H2O:Insoluble,10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.94 mM),DMSO:25 mg/mL (74.31 mM)