CBL0137, CAS [[1197996-80-7]]

Product Overview

• Article Name: CBL0137, CAS [[1197996-80-7]]
• Biozol Catalog Number: BYT-ORB1303131
• Supplier Catalog Number: orb1303131
• Alternative Catalog Number: BYT-ORB1303131-1, BYT-ORB1303131-1, BYT-ORB1303131-10, BYT-ORB1303131-100, BYT-ORB1303131-25, BYT-ORB1303131-5, BYT-ORB1303131-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: NFkB, NF-kB, NFkappaB, NF-kappaB, p53, CBLC 137, CBL0137, CBL-0137, CBLC137, CBLC-137, CBL 0137, Curaxin 137

Product Description

CBL0137 is a metabolically stable curaxin that potently activates p53 and inhibits NF-kappaB by inactivating the FACT complex. It demonstrates broad in vivo anticancer activity, eradicates resistant cancer stem cells, and synergizes with gemcitabine in preclinical pancreatic cancer models.

Product Properties

• Molecular Weight: 336.43
• Purity: 99.68% (May vary between batches)
• CAS Number: [1197996-80-7]
• Formula: C21H24N2O2
• Target: NF-kappaB,Histone Acetyltransferase,p53,MDM-2/p53

Application Notes

• Application Notes: Solubility: H2O:Insoluble,10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.94 mM),DMSO:25 mg/mL (74.31 mM)