SGC2085 is a potent and selective CARM1 inhibitor (IC50 = 50 nM) with >100-fold selectivity over other PRMTs. It is a valuable chemical probe for studying CARM1s role in Wnt/beta-catenin signaling in colorectal cancer, estrogen-dependent breast cancer growth, and in vivo proliferation of myeloid leukemia cells.
Molekulargewicht:
348.87
Reinheit:
99.91% (May vary between batches)
CAS Nummer:
[1821908-49-9]
Formel:
C19H24N2O2HCl
Target-Kategorie:
Histone Methyltransferase
Anwendungsbeschreibung:
Solubility: DMSO:55 mg/mL (157.65 mM)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten