SGC2085 is a potent and selective CARM1 inhibitor (IC50 = 50 nM) with >100-fold selectivity over other PRMTs. It is a valuable chemical probe for studying CARM1s role in Wnt/beta-catenin signaling in colorectal cancer, estrogen-dependent breast cancer growth, and in vivo proliferation of myeloid leukemia cells.
Molecular Weight:
348.87
Purity:
99.91% (May vary between batches)
CAS Number:
[1821908-49-9]
Formula:
C19H24N2O2HCl
Target:
Histone Methyltransferase
Application Notes:
Solubility: DMSO:55 mg/mL (157.65 mM)
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