Onatasertib, CAS [[1228013-30-6]]

Produktübersicht

• Artikelname: Onatasertib, CAS [[1228013-30-6]]
• Artikelnummer: BYT-ORB1304293
• Hersteller Artikelnummer: orb1304293
• Alternativnummer: BYT-ORB1304293-1, BYT-ORB1304293-1, BYT-ORB1304293-10, BYT-ORB1304293-100, BYT-ORB1304293-25, BYT-ORB1304293-5, BYT-ORB1304293-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: mTOR, inhibit, Onatasertib, FLT4, Inhibitor, Mammalian target of Rapamycin, DNAPK, DNA-PK, CC223, CC-223, CC 223, Apoptosis, ATG 008, ATG008, ATG-008, cFms, c-Fms, PI3K-alpha

Produktbeschreibung

Onatasertib (CC223) is a potent and selective oral mTOR kinase inhibitor with an IC50 of 16 nM, showing over 150-fold selectivity against PI3Kalpha. It suppresses tumor cell proliferation and induces apoptosis, demonstrating antitumor activity in preclinical in vitro and in vivo cancer models.

Produkteigenschaften

• Molekulargewicht: 397.47
• Reinheit: 99.93% (May vary between batches)
• CAS Nummer: [1228013-30-6]
• Formel: C21H27N5O3
• Target-Kategorie: PI3K,Apoptosis,mTOR,DNA-PK,FLT,c-Fms

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: DMSO:70 mg/mL (176.11 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.03 mM),Ethanol:73 mg/mL (183.66 mM),H2O:< 1 mg/mL (insoluble or slightly soluble)