Onatasertib, CAS [[1228013-30-6]]

Product Overview

• Article Name: Onatasertib, CAS [[1228013-30-6]]
• Biozol Catalog Number: BYT-ORB1304293
• Supplier Catalog Number: orb1304293
• Alternative Catalog Number: BYT-ORB1304293-1, BYT-ORB1304293-1, BYT-ORB1304293-10, BYT-ORB1304293-100, BYT-ORB1304293-25, BYT-ORB1304293-5, BYT-ORB1304293-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: mTOR, inhibit, Onatasertib, FLT4, Inhibitor, Mammalian target of Rapamycin, DNAPK, DNA-PK, CC223, CC-223, CC 223, Apoptosis, ATG 008, ATG008, ATG-008, cFms, c-Fms, PI3K-alpha

Product Description

Onatasertib (CC223) is a potent and selective oral mTOR kinase inhibitor with an IC50 of 16 nM, showing over 150-fold selectivity against PI3Kalpha. It suppresses tumor cell proliferation and induces apoptosis, demonstrating antitumor activity in preclinical in vitro and in vivo cancer models.

Product Properties

• Molecular Weight: 397.47
• Purity: 99.93% (May vary between batches)
• CAS Number: [1228013-30-6]
• Formula: C21H27N5O3
• Target: PI3K,Apoptosis,mTOR,DNA-PK,FLT,c-Fms

Application Notes

• Application Notes: Solubility: DMSO:70 mg/mL (176.11 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.03 mM),Ethanol:73 mg/mL (183.66 mM),H2O:< 1 mg/mL (insoluble or slightly soluble)