PHPS1 is a potent and selective Shp2 inhibitor that suppresses the oncogenic Shp2-E76K mutant-driven Erk1/2 activation. It effectively inhibits the anchorage-independent proliferation of various human cancer cell lines in vitro, making it a valuable chemical probe for studying Shp2 signaling in oncology research.
Molekulargewicht:
465.44
Reinheit:
99.77% (May vary between batches)
CAS Nummer:
[314291-83-3]
Formel:
C21H15N5O6S
Target-Kategorie:
Phosphatase
Anwendungsbeschreibung:
Solubility: DMSO:16.25 mg/mL (34.91 mM)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten