11-Deoxojervine, Cyclopamine, inhibit, Hedgehog, Inhibitor, EndogenousMetabolite, Endogenous Metabolite, Smoothened, Smo
Cyclopamine is a steroidal jerveratrum alkaloid that acts as a Smoothened (Smo) antagonist, with an IC50 of 46 nM in TM3Hh12 cells. It is a critical research tool for studying the Hedgehog signaling pathway in both in vitro and in vivo models of development and cancer.
Molekulargewicht:
411.62
Reinheit:
99.66% (May vary between batches)
CAS Nummer:
[4449-51-8]
Formel:
C27H41NO2
Target-Kategorie:
Smo,Endogenous Metabolite,Hedgehog/Smoothened
Anwendungsbeschreibung:
Solubility: DMSO:4.12 mg/mL (10.01 mM)
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