Cyclopamine, CAS [[4449-51-8]]

Product Overview

• Article Name: Cyclopamine, CAS [[4449-51-8]]
• Biozol Catalog Number: BYT-ORB1304971
• Supplier Catalog Number: orb1304971
• Alternative Catalog Number: BYT-ORB1304971-1, BYT-ORB1304971-10, BYT-ORB1304971-100, BYT-ORB1304971-25, BYT-ORB1304971-5, BYT-ORB1304971-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: 11-Deoxojervine, Cyclopamine, inhibit, Hedgehog, Inhibitor, EndogenousMetabolite, Endogenous Metabolite, Smoothened, Smo

Product Description

Cyclopamine is a steroidal jerveratrum alkaloid that acts as a Smoothened (Smo) antagonist, with an IC50 of 46 nM in TM3Hh12 cells. It is a critical research tool for studying the Hedgehog signaling pathway in both in vitro and in vivo models of development and cancer.

Product Properties

• Molecular Weight: 411.62
• Purity: 99.66% (May vary between batches)
• CAS Number: [4449-51-8]
• Formula: C27H41NO2
• Target: Smo,Endogenous Metabolite,Hedgehog/Smoothened

Application Notes

• Application Notes: Solubility: DMSO:4.12 mg/mL (10.01 mM)