Tandutinib, CAS [[387867-13-2]]
Artikelnummer:
BYT-ORB1307840
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| Artikelname: | Tandutinib, CAS [[387867-13-2]] |
| Artikelnummer: | BYT-ORB1307840 |
| Hersteller Artikelnummer: | orb1307840 |
| Alternativnummer: | BYT-ORB1307840-1,BYT-ORB1307840-100,BYT-ORB1307840-200,BYT-ORB1307840-25,BYT-ORB1307840-50 |
| Hersteller: | Biorbyt |
| Kategorie: | Biochemikalien |
| Alternative Synonym: | CT 53518, CT53518, CT-53518, CSF-1R, CSF1R, Cluster of differentiation antigen 135, CD135, CD117, c-Kit, cKit, Acute, blood-brain, Apoptosis, barrier, autophosphorylation, NSC 726292, Inhibitor, myelogenous, inhibit, MLN518, MLN-518, MLN 518, NSC726292, NSC-726292, PDGFR, Platelet-derived growth factor receptor, FLT3-ITD, FLT3, Fms like tyrosine kinase 3, MAP, leukemia, Src, SCFR, Tandutinib, PI3, PDGFRbeta |
| Tandutinib (MLN518) is a potent and selective FLT3 inhibitor (IC50 = 0.22 µM) with additional activity against c-Kit and PDGFR. It demonstrates significant selectivity over CSF-1R, FGFR, EGFR, and KDR. This small molecule is a valuable research tool for studying FLT3-driven hematological cancers in both cellular and animal models. |
| Molekulargewicht: | 562.7 |
| Reinheit: | 99.92% (May vary between batches) |
| CAS Nummer: | [387867-13-2] |
| Formel: | C31H42N6O4 |
| Target-Kategorie: | FLT,Src,CSF-1R,c-Kit,PDGFR,Apoptosis |
| Anwendungsbeschreibung: | Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.55 mM),Ethanol:6 mg/mL (10.66 mM),DMSO:50 mg/mL (88.86 mM) |
