Tandutinib, CAS [[387867-13-2]]

Product Overview

• Article Name: Tandutinib, CAS [[387867-13-2]]
• Biozol Catalog Number: BYT-ORB1307840
• Supplier Catalog Number: orb1307840
• Alternative Catalog Number: BYT-ORB1307840-1,BYT-ORB1307840-100,BYT-ORB1307840-200,BYT-ORB1307840-25,BYT-ORB1307840-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: CT 53518, CT53518, CT-53518, CSF-1R, CSF1R, Cluster of differentiation antigen 135, CD135, CD117, c-Kit, cKit, Acute, blood-brain, Apoptosis, barrier, autophosphorylation, NSC 726292, Inhibitor, myelogenous, inhibit, MLN518, MLN-518, MLN 518, NSC726292, NSC-726292, PDGFR, Platelet-derived growth factor receptor, FLT3-ITD, FLT3, Fms like tyrosine kinase 3, MAP, leukemia, Src, SCFR, Tandutinib, PI3, PDGFRbeta

Product Description

Tandutinib (MLN518) is a potent and selective FLT3 inhibitor (IC50 = 0.22 µM) with additional activity against c-Kit and PDGFR. It demonstrates significant selectivity over CSF-1R, FGFR, EGFR, and KDR. This small molecule is a valuable research tool for studying FLT3-driven hematological cancers in both cellular and animal models.

Product Properties

• Molecular Weight: 562.7
• Purity: 99.92% (May vary between batches)
• CAS Number: [387867-13-2]
• Formula: C31H42N6O4
• Target: FLT,Src,CSF-1R,c-Kit,PDGFR,Apoptosis

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.55 mM),Ethanol:6 mg/mL (10.66 mM),DMSO:50 mg/mL (88.86 mM)