Dasatinib monohydrate, CAS [[863127-77-9]]

Artikelnummer: BYT-ORB1308590
Artikelname: Dasatinib monohydrate, CAS [[863127-77-9]]
Artikelnummer: BYT-ORB1308590
Hersteller Artikelnummer: orb1308590
Alternativnummer: BYT-ORB1308590-1, BYT-ORB1308590-1, BYT-ORB1308590-100, BYT-ORB1308590-50, BYT-ORB1308590-500
Hersteller: Biorbyt
Kategorie: Biochemikalien
Alternative Synonym: WiDr, Src, prostate, K562, inhibit, PC3, orally, Inhibitor, EphA2, Ephrin Receptor, EphrinReceptor, Dasatinib, Dasatinib monohydrate, Dasatinib Monohydrate, colon, cKit, c-Kit (D816V), c-Kit (wt), CML, breast, active, Abl, antitumor, antiproliferative, Apoptosis, Autophagy, BMS 354825, BMS 354825 Monohydrate, BMS354825 Monohydrate, BMS-354825 Monohydrate, BMS354825, BMS-354825, BcrAbl, Bcr-Abl
Dasatinib monohydrate is a potent, orally available SRC-family and BCR-ABL tyrosine kinase inhibitor. It is widely used in research to overcome imatinib resistance in CML models, with applications in both in vitro cellular assays and in vivo xenograft studies for investigating leukemia pathogenesis and treatment.
Molekulargewicht: 506.03
Reinheit: >99.99% (May vary between batches)
CAS Nummer: [863127-77-9]
Formel: C22H28ClN7O3S
Target-Kategorie: Src,Bcr-Abl,c-Kit,Ephrin Receptor,Apoptosis,Autophagy
Anwendungsbeschreibung: Solubility: Ethanol:< 1 mg/mL (insoluble or slightly soluble),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.95 mM),H2O:< 1 mg/mL (insoluble or slightly soluble),DMSO:123.75 mg/mL (244.55 mM)