Dasatinib monohydrate, CAS [[863127-77-9]]

Product Overview

• Article Name: Dasatinib monohydrate, CAS [[863127-77-9]]
• Biozol Catalog Number: BYT-ORB1308590
• Supplier Catalog Number: orb1308590
• Alternative Catalog Number: BYT-ORB1308590-1, BYT-ORB1308590-1, BYT-ORB1308590-100, BYT-ORB1308590-50, BYT-ORB1308590-500
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: WiDr, Src, prostate, K562, inhibit, PC3, orally, Inhibitor, EphA2, Ephrin Receptor, EphrinReceptor, Dasatinib, Dasatinib monohydrate, Dasatinib Monohydrate, colon, cKit, c-Kit (D816V), c-Kit (wt), CML, breast, active, Abl, antitumor, antiproliferative, Apoptosis, Autophagy, BMS 354825, BMS 354825 Monohydrate, BMS354825 Monohydrate, BMS-354825 Monohydrate, BMS354825, BMS-354825, BcrAbl, Bcr-Abl

Product Description

Dasatinib monohydrate is a potent, orally available SRC-family and BCR-ABL tyrosine kinase inhibitor. It is widely used in research to overcome imatinib resistance in CML models, with applications in both in vitro cellular assays and in vivo xenograft studies for investigating leukemia pathogenesis and treatment.

Product Properties

• Molecular Weight: 506.03
• Purity: >99.99% (May vary between batches)
• CAS Number: [863127-77-9]
• Formula: C22H28ClN7O3S
• Target: Src,Bcr-Abl,c-Kit,Ephrin Receptor,Apoptosis,Autophagy

Application Notes

• Application Notes: Solubility: Ethanol:< 1 mg/mL (insoluble or slightly soluble),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.95 mM),H2O:< 1 mg/mL (insoluble or slightly soluble),DMSO:123.75 mg/mL (244.55 mM)