Dasatinib, CAS [[302962-49-8]]

Produktübersicht

• Artikelname: Dasatinib, CAS [[302962-49-8]]
• Artikelnummer: BYT-ORB1308592
• Hersteller Artikelnummer: orb1308592
• Alternativnummer: BYT-ORB1308592-25, BYT-ORB1308592-5
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: BcrAbl, Bcr-Abl, BMS 354825, BMS354825, BMS-354825, Autophagy, Apoptosis, antiproliferative, antitumor, active, Abl, Dasatinib, c-Kit (wt), c-Kit (D816V), cKit, breast, CML, colon, orally, PC3, inhibit, K562, Inhibitor, WiDr, Src, prostate

Produktbeschreibung

Dasatinib is an orally bioavailable, ATP-competitive tyrosine kinase inhibitor targeting Src and Bcr-Abl with high potency (Ki=16/30 pM). It is widely used in leukemia and lymphoma research, demonstrating antitumor efficacy in both in vitro cellular assays and in vivo animal models of cancer.

Produkteigenschaften

• Molekulargewicht: 488.01
• Reinheit: 99.89% (May vary between batches)
• CAS Nummer: [302962-49-8]
• Formel: C22H26ClN7O2S
• Target-Kategorie: Bcr-Abl,Apoptosis,c-Kit,Autophagy,Src

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: DMSO:262.5 mg/mL (537.9 mM),Ethanol:< 1 mg/mL (insoluble or slightly soluble),H2O:< 1 mg/mL (insoluble or slightly soluble),10% DMSO+40% PEG300+5% Tween 80+45% Saline:9.1 mg/mL (18.65 mM)