Dasatinib, CAS [[302962-49-8]]

Product Overview

• Article Name: Dasatinib, CAS [[302962-49-8]]
• Biozol Catalog Number: BYT-ORB1308592
• Supplier Catalog Number: orb1308592
• Alternative Catalog Number: BYT-ORB1308592-25, BYT-ORB1308592-5
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: BcrAbl, Bcr-Abl, BMS 354825, BMS354825, BMS-354825, Autophagy, Apoptosis, antiproliferative, antitumor, active, Abl, Dasatinib, c-Kit (wt), c-Kit (D816V), cKit, breast, CML, colon, orally, PC3, inhibit, K562, Inhibitor, WiDr, Src, prostate

Product Description

Dasatinib is an orally bioavailable, ATP-competitive tyrosine kinase inhibitor targeting Src and Bcr-Abl with high potency (Ki=16/30 pM). It is widely used in leukemia and lymphoma research, demonstrating antitumor efficacy in both in vitro cellular assays and in vivo animal models of cancer.

Product Properties

• Molecular Weight: 488.01
• Purity: 99.89% (May vary between batches)
• CAS Number: [302962-49-8]
• Formula: C22H26ClN7O2S
• Target: Bcr-Abl,Apoptosis,c-Kit,Autophagy,Src

Application Notes

• Application Notes: Solubility: DMSO:262.5 mg/mL (537.9 mM),Ethanol:< 1 mg/mL (insoluble or slightly soluble),H2O:< 1 mg/mL (insoluble or slightly soluble),10% DMSO+40% PEG300+5% Tween 80+45% Saline:9.1 mg/mL (18.65 mM)