DNAMethyltransferase, DNMT1, DNMT1 inhibitor, DNMTs, DNA Methyltransferase, DNA MTases, cancer, mDNMT3A, Inhibitor, hDNMT1, inhibit, SW155246, SW-155246, SW 155246
SW155246 is a potent and selective DNMT1 inhibitor (IC50 = 1.2 µM) that reactivates silenced tumor suppressor genes, such as RASSF1, in cellular models like A549 lung carcinoma cells. This compound is a valuable chemical probe for epigenetic research, enabling the study of DNA methylations role in cancer biology and gene expression both in vitro and in vivo.
Molekulargewicht:
378.79
Reinheit:
98.99% (May vary between batches)
CAS Nummer:
[420092-79-1]
Formel:
C16H11ClN2O5S
Target-Kategorie:
DNA Methyltransferase
Anwendungsbeschreibung:
Solubility: DMSO:50 mg/mL (132 mM)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten