SW155246, CAS [[420092-79-1]]

Product Overview

• Article Name: SW155246, CAS [[420092-79-1]]
• Biozol Catalog Number: BYT-ORB1685336
• Supplier Catalog Number: orb1685336
• Alternative Catalog Number: BYT-ORB1685336-1, BYT-ORB1685336-10, BYT-ORB1685336-100, BYT-ORB1685336-25, BYT-ORB1685336-5, BYT-ORB1685336-50, BYT-ORB1685336-500
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: DNAMethyltransferase, DNMT1, DNMT1 inhibitor, DNMTs, DNA Methyltransferase, DNA MTases, cancer, mDNMT3A, Inhibitor, hDNMT1, inhibit, SW155246, SW-155246, SW 155246

Product Description

SW155246 is a potent and selective DNMT1 inhibitor (IC50 = 1.2 µM) that reactivates silenced tumor suppressor genes, such as RASSF1, in cellular models like A549 lung carcinoma cells. This compound is a valuable chemical probe for epigenetic research, enabling the study of DNA methylations role in cancer biology and gene expression both in vitro and in vivo.

Product Properties

• Molecular Weight: 378.79
• Purity: 98.99% (May vary between batches)
• CAS Number: [420092-79-1]
• Formula: C16H11ClN2O5S
• Target: DNA Methyltransferase

Application Notes

• Application Notes: Solubility: DMSO:50 mg/mL (132 mM)