TH1760, CAS [[2567914-01-4]]

Produktübersicht

• Artikelname: TH1760, CAS [[2567914-01-4]]
• Artikelnummer: BYT-ORB1685551
• Hersteller Artikelnummer: orb1685551
• Alternativnummer: BYT-ORB1685551-10, BYT-ORB1685551-100, BYT-ORB1685551-25, BYT-ORB1685551-5, BYT-ORB1685551-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: TH1760, TH-1760, TH 1760, NUDIX hydrolase, NUDIXhydrolase, NUDT15, MKB

Produktbeschreibung

TH1760 (MKB) is a potent NUDT15 inhibitor (IC50=25 nM) that increases cellular 6-thio-(d)GTP incorporation, thereby sensitizing cells to 6-thioguanine. This compound enhances the anti-leukemic activity of thiopurines in research models, supporting its investigation in hematological malignancies.

Produkteigenschaften

• Molekulargewicht: 426.45
• Reinheit: 97.31% (May vary between batches)
• CAS Nummer: [2567914-01-4]
• Formel: C20H18N4O5S
• Target-Kategorie: DNA/RNA Synthesis,Others,NUDIX hydrolase

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: DMSO:1.8 mg/mL (4.22 mM)