TH1760, CAS [[2567914-01-4]]

Product Overview

• Article Name: TH1760, CAS [[2567914-01-4]]
• Biozol Catalog Number: BYT-ORB1685551
• Supplier Catalog Number: orb1685551
• Alternative Catalog Number: BYT-ORB1685551-10, BYT-ORB1685551-100, BYT-ORB1685551-25, BYT-ORB1685551-5, BYT-ORB1685551-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: TH1760, TH-1760, TH 1760, NUDIX hydrolase, NUDIXhydrolase, NUDT15, MKB

Product Description

TH1760 (MKB) is a potent NUDT15 inhibitor (IC50=25 nM) that increases cellular 6-thio-(d)GTP incorporation, thereby sensitizing cells to 6-thioguanine. This compound enhances the anti-leukemic activity of thiopurines in research models, supporting its investigation in hematological malignancies.

Product Properties

• Molecular Weight: 426.45
• Purity: 97.31% (May vary between batches)
• CAS Number: [2567914-01-4]
• Formula: C20H18N4O5S
• Target: DNA/RNA Synthesis,Others,NUDIX hydrolase

Application Notes

• Application Notes: Solubility: DMSO:1.8 mg/mL (4.22 mM)