GSK215, CAS [[2743427-26-9]]

Produktübersicht

• Artikelname: GSK215, CAS [[2743427-26-9]]
• Artikelnummer: BYT-ORB1685568
• Hersteller Artikelnummer: orb1685568
• Alternativnummer: BYT-ORB1685568-1, BYT-ORB1685568-10, BYT-ORB1685568-100, BYT-ORB1685568-25, BYT-ORB1685568-5, BYT-ORB1685568-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: GSK 215, GSK215, GSK-215, FAK

Produktbeschreibung

GSK215 is a potent and selective PROTAC degrader of focal adhesion kinase (FAK), achieving degradation with a pDC50 of 8.4. It is built from the FAK inhibitor VS-4718 and a VHL E3 ligase ligand, enabling rapid and sustained FAK loss, a valuable tool for studying FAK biology in cancer and metastasis research both in vitro and in vivo.

Produkteigenschaften

• Molekulargewicht: 985.13
• Reinheit: 99.30% (May vary between batches)
• CAS Nummer: [2743427-26-9]
• Formel: C50H59F3N10O6S
• Target-Kategorie: FAK,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (5.08 mM),DMSO:225 mg/mL (228.4 mM)