GSK215, CAS [[2743427-26-9]]

Product Overview

• Article Name: GSK215, CAS [[2743427-26-9]]
• Biozol Catalog Number: BYT-ORB1685568
• Supplier Catalog Number: orb1685568
• Alternative Catalog Number: BYT-ORB1685568-1, BYT-ORB1685568-10, BYT-ORB1685568-100, BYT-ORB1685568-25, BYT-ORB1685568-5, BYT-ORB1685568-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: GSK 215, GSK215, GSK-215, FAK

Product Description

GSK215 is a potent and selective PROTAC degrader of focal adhesion kinase (FAK), achieving degradation with a pDC50 of 8.4. It is built from the FAK inhibitor VS-4718 and a VHL E3 ligase ligand, enabling rapid and sustained FAK loss, a valuable tool for studying FAK biology in cancer and metastasis research both in vitro and in vivo.

Product Properties

• Molecular Weight: 985.13
• Purity: 99.30% (May vary between batches)
• CAS Number: [2743427-26-9]
• Formula: C50H59F3N10O6S
• Target: FAK,PROTACs

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (5.08 mM),DMSO:225 mg/mL (228.4 mM)