AT533, AT-533, AT 533, Benzamide,2[(trans4hydroxycyclohexyl)amino]4(4,5,6,7tetrahydro3,6,6trimethyl4oxo1Hindazol1yl), HSV, HSP90
AT-533 is a dual Hsp90 and HSV inhibitor that suppresses tumor growth and angiogenesis by blocking the HIF-1alpha/VEGF/VEGFR-2 signaling axis and downstream pathways like Erk1/2 and Akt/mTOR. It has demonstrated anti-angiogenic activity in vitro by inhibiting HUVEC migration, invasion, and tube formation, supporting its research application in oncology and virology studies.