AT-533, CAS [[908112-37-8]]

Product Overview

• Article Name: AT-533, CAS [[908112-37-8]]
• Biozol Catalog Number: BYT-ORB1685570
• Supplier Catalog Number: orb1685570
• Alternative Catalog Number: BYT-ORB1685570-1, BYT-ORB1685570-1, BYT-ORB1685570-10, BYT-ORB1685570-100, BYT-ORB1685570-200, BYT-ORB1685570-25, BYT-ORB1685570-5, BYT-ORB1685570-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: AT533, AT-533, AT 533, Benzamide,2[(trans4hydroxycyclohexyl)amino]4(4,5,6,7tetrahydro3,6,6trimethyl4oxo1Hindazol1yl), HSV, HSP90

Product Description

AT-533 is a dual Hsp90 and HSV inhibitor that suppresses tumor growth and angiogenesis by blocking the HIF-1alpha/VEGF/VEGFR-2 signaling axis and downstream pathways like Erk1/2 and Akt/mTOR. It has demonstrated anti-angiogenic activity in vitro by inhibiting HUVEC migration, invasion, and tube formation, supporting its research application in oncology and virology studies.

Product Properties

• Molecular Weight: 410.51
• Purity: 99.67% (May vary between batches)
• CAS Number: [908112-37-8]
• Formula: C23H30N4O3
• Target: HIF/HIF Prolyl-Hydroxylase,FAK,Akt,VEGFR,HSP,ERK,NF-kappaB,HSV

Application Notes

• Application Notes: Solubility: DMSO:60 mg/mL (146.16 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.87 mM)