JAK3-IN-14 is a potent, selective, and orally bioavailable small molecule inhibitor of FLT3, demonstrating nanomolar IC50 values against FLT3-WT, FLT3-D835Y, and FLT3-D835H mutants. It is a valuable research tool for investigating FLT3-driven pathologies, such as acute myeloid leukemia (AML), in both cellular and animal models.
Molekulargewicht:
287.32
Reinheit:
98.98% (May vary between batches)
CAS Nummer:
[454234-24-3]
Formel:
C18H13N3O
Target-Kategorie:
JAK,FLT
Anwendungsbeschreibung:
Solubility: DMSO:50 mg/mL (174.02 mM)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten